Our lab's research examines the neurobiology of autism by using a model of Fragile X syndrome, which is the number one genetic cause of intellectual disability. Fragile X rats are created by modifying the Fmr1 gene (Fmr1 knock out) which results in the loss of FMR protein. Projects include looking at differences between control and Fmr 1 KO rats in cognitive attention tasks, repetitive behaviors, and motor coordination. Additionally, we are use electrophysiology to record from the medial prefrontal cortex during cognitive performance in the Fmr1 knock out rat.  We are interested in understanding change across the life-span and have projects that examine adolescent development as well as in aged animals. We also use transcranial magnetic stimulation (TMS) to regulate brain activity, improve cognition and reduce neural pathology.